Catalysis-Induced Phase Separation and Autoregulation of Enzymatic Activity.
Physical review letters 129:15 (2022) 158101
Abstract:
We present a thermodynamically consistent model describing the dynamics of a multicomponent mixture where one enzyme component catalyzes a reaction between other components. We find that the catalytic activity alone can induce phase separation for sufficiently active systems and large enzymes, without any equilibrium interactions between components. In the limit of fast reaction rates, binodal lines can be calculated using a mapping to an effective free energy. We also explain how this catalysis-induced phase separation can act to autoregulate the enzymatic activity, which points at the biological relevance of this phenomenon.Optimal navigation of microswimmers in complex and noisy environments
New Journal of Physics IOP Publishing 24:9 (2022) 093037
Sustained unidirectional rotation of a self-organized DNA rotor on a nanopore
Nature Physics Springer Nature 18:9 (2022) 1105-1111
Effervescent waves in a binary mixture with non-reciprocal couplings
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A Synthetic Minimal Beating Axoneme.
Small (Weinheim an der Bergstrasse, Germany) 18:32 (2022) e2107854