Publications by Sonia Antoranz Contera

Developing a single-molecule fluorescence tool to quantify DNA damage

Biophysical Journal Elsevier 110 (2016) p164a-

Quantification of DNA damage is an important technique for medical physics, for example to assess damage caused by the quinolone antibiotics, or to examine the effects of novel cancer treatments such as low-temperature plasma therapy on healthy or tumorous cells. Existing damage quantification techniques such as the alkaline comet assay [1] are often subjective in their results, especially at higher damage levels. Methods using immunofluorescence [2] often lose information due to the three dimensional nature of the cell.

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